Copy-number variation 
¶
Agentic variant analysis of the 1000 Genomes Project — VCF → Parquet curation under a schema contract, then Polars / DuckDB / PyArrow queries and agent-tracked genomic-band analyses.
Write-up: Agentic variant analysis of the 1000 Genomes Project
Instance: laminlabs/1000genomes · Projects: Lakehouse benchmarks · Agentic workflows
Agentic analyses¶
Example task: count variants in a genomic band (chr1:150–200 Mb) — raw Parquet files vs. collection schema contract (blog Fig. 1).
Approach |
Script |
Agent run |
|---|---|---|
Via collection |
||
Via raw files |