Re-constructing Schmidt et al. (2022)

This use-case re-constructs a result of the research project of Schmidt el al. (2022) via several scripts & notebooks.

A genome-wide phenotypic CRISPRa screen was used to find transcriptional cell states that correlate with causal drivers of proteomic IFNG expression.

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To understand how this result was obtained, one can look at the lineage:

You can explore it here together with code and data artifacts.

You can also see all code and how it can be executed in build.yml here:

laminlabs/schmidt22