`nf-lamin` plugin reference ¶

Configuration¶

Basic Configuration¶

Add the following block to your nextflow.config:

plugins {
  id 'nf-lamin'
}

lamin {
  instance = "<your-lamin-org>/<your-lamin-instance>"
  api_key = secrets.LAMIN_API_KEY
  project_uids = ['proj123456789012'] // optional
  ulabel_uids = ['ulab123456789012']  // optional
}

Settings:

lamin.instance: (Required) The LaminDB instance to connect to, in the format organization/instance.
lamin.api_key: (Required) Your Lamin Hub API key. It is strongly recommended to set this using nextflow secrets.
lamin.project_uids: (Optional) List of project UIDs to link to all artifacts, runs, and transforms.
lamin.ulabel_uids: (Optional) List of ulabel UIDs to link to all artifacts, runs, and transforms.

Alternatively, you can use environment variables, though this is less secure:

export LAMIN_CURRENT_INSTANCE="laminlabs/lamindata"
export LAMIN_API_KEY="your-lamin-api-key"
export LAMIN_CURRENT_PROJECT="proj123456789012"  # Project UID

Advanced Configuration¶

The plugin offers advanced settings for custom deployments or for tuning its behavior.

lamin {
  // ... basic settings ...

  // Root-level UIDs apply to all artifacts, runs, and transforms
  project_uids = ['proj123456789012']
  ulabel_uids = ['ulab123456789012']

  // The environment name in LaminDB (e.g. "prod" or "staging")
  env = "prod"
  // Enable dry-run mode to test configuration without creating records
  dry_run = false

  // API connection settings
  api {
    // The Supabase API URL for the LaminDB instance (if env is set to "custom")
    supabase_api_url = "https://your-supabase-api-url.supabase.co"
    // The Supabase anon key for the LaminDB instance (if env is set to "custom")
    supabase_anon_key = secrets.SUPABASE_ANON_KEY
    // The number of retries for API requests
    max_retries = 3
    // The delay between retries in milliseconds
    retry_delay = 100
  }

  // Run-specific metadata linking
  run {
    project_uids = ['proj-run-specific']
    ulabel_uids = ['ulab-run-specific']
  }

  // Transform-specific metadata linking
  transform {
    project_uids = ['proj-transform-specific']
    ulabel_uids = ['ulab-transform-specific']
  }

  // Manually specify a transform UID if known (advanced users only)
  transform_uid = "your-transform-uid"
  // Manually specify a run UID if known (advanced users only)
  run_uid = "your-run-uid"
}

Artifact Tracking Configuration¶

Control which files are tracked as artifacts and attach metadata using pattern-based rules. You can configure tracking globally, or separately for inputs and outputs.

Basic Artifact Tracking¶

lamin {
  // ... instance and api_key ...

  // Control output artifact tracking
  output_artifacts {
    enabled = true
    include_pattern = '.*\\.(fastq|bam|vcf)\\.gz$'  // Only track compressed files
    exclude_pattern = '.*\\.tmp$'                   // Exclude temporary files
  }

  // Control input artifact tracking
  input_artifacts {
    enabled = true
    exclude_pattern = '.*\\.log$'  // Don't track log files as inputs
  }
}

Advanced Artifact Tracking with Rules¶

Use rules to apply different configurations based on file patterns:

lamin {
  // Root-level UIDs apply to all artifacts, runs, and transforms
  project_uids = ['global-project']
  ulabel_uids = ['project-wide-label']

  // Global artifact settings
  artifacts {
    enabled = true
  }

  // Input-specific configuration
  input_artifacts {
    enabled = true

    rules {
      reference_data {
        pattern = '.*reference.*\\.(fasta|gtf)$'
        ulabel_uids = ['reference-data-label']
        kind = 'reference'
        order = 1  // Higher priority
      }

      sample_data {
        pattern = '.*\\.fastq\\.gz$'
        ulabel_uids = ['raw-reads-label']
        project_uids = ['sequencing-project']
        kind = 'dataset'
        order = 2
      }
    }
  }

  // Output-specific configuration
  output_artifacts {
    enabled = true
    exclude_pattern = '.*\\.(log|tmp)$'  // Exclude logs and temp files

    rules {
      // Exclude work-in-progress outputs
      exclude_intermediate {
        type = 'exclude'
        pattern = '.*intermediate.*'
        order = 1
      }

      // Track final BAM files
      aligned_reads {
        pattern = '.*\\.bam$'
        ulabel_uids = ['aligned-reads-label']
        kind = 'aligned_data'
        order = 2
      }

      // Track variant calls with high priority
      variants {
        pattern = '.*\\.vcf\\.gz$'
        ulabel_uids = ['variants-label']
        project_uids = ['variant-calling-project']
        kind = 'variants'
        order = 3
      }

      // Disable tracking for specific file types
      disable_fastqc {
        enabled = false
        pattern = '.*_fastqc\\.(html|zip)$'
      }
    }
  }
}

Configuration Options¶

Global Options (apply to artifacts, input_artifacts, output_artifacts):

enabled (Boolean, default: true) - Enable or disable artifact tracking
include_pattern (String) - Java regex pattern. Files must match this pattern to be tracked
exclude_pattern (String) - Java regex pattern. Files matching this pattern will not be tracked
ulabel_uids (List or String) - ULabel UIDs to attach to all matching artifacts
project_uids (List or String) - Project UIDs to attach to all matching artifacts
kind (String) - Artifact kind (e.g., ‘dataset’, ‘model’, ‘reference’, ‘report’)
rules (Map) - Named rules for path-specific configurations

Rule Options (apply to individual rules within rules):

enabled (Boolean, default: true) - Enable or disable this rule
pattern (String, required) - Java regex pattern to match file paths
type (String, default: 'include') - Rule type: 'include' to track matching files, 'exclude' to skip them
direction (String, default: inherited) - Apply rule to 'input', 'output', or 'both'
order (Integer, default: 100) - Rule evaluation priority (lower numbers = higher priority)
ulabel_uids (List or String) - ULabel UIDs to attach to matching artifacts
project_uids (List or String) - Project UIDs to attach to matching artifacts
kind (String) - Override artifact kind for matching files

Rule Evaluation¶

Global patterns are checked first (include_pattern and exclude_pattern)
Rules are evaluated in order of priority (order field, lower numbers first)
All matching rules are processed - each can modify the tracking decision and add metadata
Later include rules can override earlier exclude rules, and vice versa
If no rules match, the file is tracked using global settings
Metadata merging: ULabels and Projects from global config and all matching rules are combined (duplicates removed)

Pattern Syntax¶

Patterns use Java regular expressions. Common patterns:

.*\\.fastq$ - Match files ending with .fastq
.*\\.fastq\\.gz$ - Match compressed FASTQ files
.*/output/.* - Match files in any output directory
.*_(R1|R2)_.* - Match paired-end read files
^(?!.*temp).*$ - Match files NOT containing “temp”

Important: Backslashes must be escaped in Groovy strings: \\. instead of \.

Examples¶

Disable all artifact tracking:

lamin {
  output_artifacts {
    enabled = false
  }
  input_artifacts {
    enabled = false
  }
}

Track only specific file types:

lamin {
  output_artifacts {
    enabled = true
    include_pattern = '.*\\.(bam|vcf\\.gz|h5ad)$'
  }
}

Exclude temporary and intermediate files:

lamin {
  output_artifacts {
    enabled = true
    exclude_pattern = '.*\\.(tmp|temp|intermediate).*'
  }
}

Different labels for different file types:

lamin {
  output_artifacts {
    rules {
      raw_data {
        pattern = '.*\\.fastq\\.gz$'
        ulabel_uids = ['raw-sequencing-data']
        kind = 'raw_reads'
      }
      processed_data {
        pattern = '.*\\.h5ad$'
        ulabel_uids = ['processed-expression-matrix']
        kind = 'expression_matrix'
      }
    }
  }
}

You can also set these using environment variables:

export LAMIN_ENV="prod"
export LAMIN_DRY_RUN="false"
export LAMIN_CURRENT_PROJECT="proj123456789012"  # Used for project_uids
export SUPABASE_API_URL="https://your-supabase-api-url.supabase.co"
export SUPABASE_ANON_KEY="your-supabase-anon-key"
export LAMIN_MAX_RETRIES=3
export LAMIN_RETRY_DELAY=100
export LAMIN_TRANSFORM_UID="your-transform-uid"
export LAMIN_RUN_UID="your-run-uid"

Advanced settings explained:

project_uids & ulabel_uids: Root-level UIDs that apply to all artifacts, runs, and transforms. Can be combined with object-specific UIDs in run and transform sections.
run & transform: Object-specific metadata linking. UIDs specified here are merged with root-level UIDs.
env: Environment selector for LaminDB instance (e.g., “prod”, “staging”, or “custom”)
dry_run: When true, the plugin validates configuration and connects to LaminDB but does not create or modify any records (transforms, runs, or artifacts). Useful for testing your setup without affecting the database.
api: Advanced API connection settings including Supabase connection details and retry behavior
- supabase_api_url & supabase_anon_key: Custom Supabase connection details (only needed if env = "custom")
- max_retries & retry_delay: Control retry behavior for API requests
transform_uid & run_uid: Manually override transform/run UIDs (advanced usage only)

Functions¶

`getRunUid()`¶

Returns the UID of the current Lamin run.

Returns: String - The run UID, or null if the plugin hasn’t initialized the run yet.

Example:

include { getRunUid } from 'plugin/nf-lamin'

workflow {
  def runUid = getRunUid()
  log.info "Current run: ${runUid}"
}

`getTransformUid()`¶

Returns the UID of the current Lamin transform.

Returns: String - The transform UID, or null if the plugin hasn’t initialized the transform yet.

Example:

include { getTransformUid } from 'plugin/nf-lamin'

workflow {
  def transformUid = getTransformUid()
  log.info "Current transform: ${transformUid}"
}

`getInstanceSlug()`¶

Returns the currently configured LaminDB instance identifier.

Returns: String - The instance slug in the format “owner/name” (e.g., “laminlabs/lamindata”), or null if not available.

Example:

include { getInstanceSlug } from 'plugin/nf-lamin'

workflow {
  def instance = getInstanceSlug()
  log.info "Connected to LaminDB instance: ${instance}"
}

Lamin URIs¶

The plugin provides native support for lamin:// URIs, allowing you to reference LaminDB artifacts directly in your Nextflow workflows using Nextflow’s standard file() function.

lamin://<owner>/<instance>/artifact/<uid>[/<subpath>]

Components:

owner - The LaminDB instance owner (organization or user)
instance - The LaminDB instance name
uid - The artifact UID (16 or 20 characters)
- 16-character base UIDs fetch the most recently updated version
- 20-character full UIDs fetch that specific version
subpath - (Optional) Path within the artifact for directories or archives

Basic Usage¶

Use lamin:// URIs with the file() function:

workflow {
  // Reference a LaminDB artifact directly by URI
  def input_file = file('lamin://laminlabs/lamindata/artifact/PnNjE93TdZGJ')

  log.info "Using artifact: ${input_file}"

  Channel.of(input_file)
    | myProcess
}

With Sub-paths¶

For artifacts that are directories or archives, reference specific files within them:

workflow {
  // Reference a specific file within an artifact directory
  def config_file = file('lamin://myorg/myinstance/artifact/abcd1234efgh5678/config/settings.yaml')

  Channel.of(config_file)
    | processConfig
}

As Workflow Parameters¶

Use lamin:// URIs as workflow parameters:

params.input = 'lamin://laminlabs/lamindata/artifact/PnNjE93TdZGJ'

workflow {
  Channel.fromPath(params.input)
    | myProcess
}

Or pass them on the command line:

nextflow run my-pipeline.nf --input 'lamin://laminlabs/lamindata/artifact/PnNjE93TdZGJ'

Requirements¶

The nf-lamin plugin must be configured with a valid API key
The workflow must have started (the plugin initializes on workflow start)
For private cloud storage, ensure your AWS/GCS credentials are configured in nextflow.config

Limitations¶

lamin:// paths are read-only - you cannot write to them
Currently uses cloud credentials from your nextflow.config (automatic credential federation from Lamin Hub is planned for a future release)

nf-lamin plugin reference ¶

Configuration¶

Basic Configuration¶

Advanced Configuration¶

Artifact Tracking Configuration¶

Basic Artifact Tracking¶

Advanced Artifact Tracking with Rules¶

Configuration Options¶

Rule Evaluation¶

Pattern Syntax¶

Examples¶

Functions¶

getRunUid()¶

getTransformUid()¶

getInstanceSlug()¶

Lamin URIs¶

Basic Usage¶

With Sub-paths¶

As Workflow Parameters¶

Requirements¶

Limitations¶

`nf-lamin` plugin reference ¶

`getRunUid()`¶

`getTransformUid()`¶

`getInstanceSlug()`¶